clinical aspects and results of lensectomy in hereditary lens subluxation

purpose: to evaluate the clinical manifestations and results of lensectomy in patients with hereditary lens subluxation at labbafinejad medical center, tehran-iran from 1996 t 2003. method: in an interventional case series, records of patients with hereditary lens subluxation who had undergone lensectomy were reviewed. patients with at least 6 months of follow up were included. background disease, best corrected visual acuity (bcva) before and after surgery, intraocular pressure (iop), and post-operative refraction and complications were evaluated. results: the study was performed on 87 eyes of 49 patients including 27 male and 22 female subjects. mean follow up was 20 ± 18 months. background diseases included: marfan syndrome (79.5%), weill-marchesani syndrome (8.2%), simple ectopia lentis (8.2%), and homocystinuria (4.1%). the most common indication for surgery was non-correctable refractive error (92.1%). mean bcva was 1.13 logmar preoperatively which improved to 0.26 log mar post-operatively (p< 0.001). bcva better than 20/40 was achieved in 82.8% of cases after surgery. angle-supported anterior chamber intraocular lens (ac iol) was implanted in 85.1% of the eyes. prophylactic band was applied in 63 eyes (72.4%). retinal detachment developed in four eyes, which was successfully treated. conclusions: lensectomy with implantation of angle-supported ac iol in patients with hereditary subluxated lens will improve vision significantly without significant complications.